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Intracellular acidification is required for full activation of the sweet taste receptor by miraculin

Acidification of the glycoprotein, miraculin (MCL), induces sweet taste in humans, but not in mice. The sweet taste induced by MCL is more intense when acidification occurs with weak acids as opposed to strong acids. MCL interacts with the human sweet receptor subunit hTAS1R2, but the mechanisms by...

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Bibliografiska uppgifter
I publikationen:Sci Rep
Huvudupphovsmän: Sanematsu, Keisuke, Kitagawa, Masayuki, Yoshida, Ryusuke, Nirasawa, Satoru, Shigemura, Noriatsu, Ninomiya, Yuzo
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group 2016
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4785348/
https://ncbi.nlm.nih.gov/pubmed/26960429
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep22807
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