CXCR4 Protein Epitope Mimetic Antagonist, POL5551, Disrupts Metastasis and Enhances Chemotherapy Effect in Triple Negative Breast Cancer

The SDF-1-receptor CXCR4 has been associated with early metastasis and poorer prognosis in breast cancers, especially the most aggressive triple negative subtype. In line with previous reports, we found that tumoral CXCR4 expression in patients with locally advanced breast cancer was associated with...

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Bibliografski detalji
Izdano u:Mol Cancer Ther
Glavni autori: Xiang, Jingyu, Hurchla, Michelle A., Fontana, Francesca, Su, Xinming, Amend, Sarah R., Esser, Alison K., Douglas, Garry J., Mudalagiriyappa, Chidananda, Luker, Kathryn E., Pluard, Timothy, Ademuyiwa, Foluso O., Romagnoli, Barbara, Tuffin, Gérald, Chevalier, Eric, Luker, Gary D., Bauer, Michael, Zimmermann, Johann, Aft, Rebecca L., Dembowsky, Klaus, Weilbaecher, Katherine N.
Format: Artigo
Jezik:Inglês
Izdano: 2015
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4784694/
https://ncbi.nlm.nih.gov/pubmed/26269605
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-15-0252
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