The novel CXCR4 antagonist POL5551 mobilizes hematopoietic stem and progenitor cells with greater efficiency than Plerixafor

Mobilized blood has supplanted bone marrow (BM) as the primary source of hematopoietic stem cells for autologous and allogeneic stem cell transplantation. Pharmacologically enforced egress of hematopoietic stem cells from BM, or mobilization, has been achieved by directly or indirectly targeting the...

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Autors principals: Karpova, D, Dauber, K, Spohn, G, Chudziak, D, Wiercinska, E, Schulz, M, Pettit, A R, Levesque, J P, Romagnoli, B, Patel, K, Chevalier, E, Dembowsky, K, Bonig, H
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2013
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3865534/
https://ncbi.nlm.nih.gov/pubmed/24072044
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/leu.2013.266
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