Protective effect of a Protein Epitope Mimetic CCR10 antagonist, POL7085, in a model of allergic eosinophilic airway inflammation

Por Daubeuf, François, Jung, Françoise, Douglas, Garry J., Chevalier, Eric, Frossard, Nelly
Publicado no Respir Res (2015)

ET-51 COMBINED THERAPY WITH A NOVEL CXCR4 ANTAGONIST AND AN ANTI-VEGF ANTIBODY IMPAIRS THE GROWTH OF GLIOMAS

Por Sarfraz, Yasmeen, Alotaibi, Fawaz M., Ortenzi, Valerio, Tayyib, Awab T., Douglas, Garry J., Chevalier, Eric, Romagnoli, Barbara, Tuffin, Gérald, Gagner, Jean-Pierre, Zagzag, David
Publicado em 2014

CXCR7-dependent angiogenic mononuclear cell trafficking regulates tumor progression in multiple myeloma

Por Azab, Abdel Kareem, Sahin, Ilyas, Azab, Feda, Moschetta, Michele, Mishima, Yuji, Burwick, Nicholas, Zimmermann, Johann, Romagnoli, Barbara, Patel, Kalpana, Chevalier, Eric, Roccaro, Aldo M., Ghobrial, Irene M.
Publicado em 2014

Mobilization of hematopoietic stem cells with the novel CXCR4 antagonist POL6326 (balixafortide) in healthy volunteers—results of a dose escalation trial

Por Karpova, Darja, Bräuninger, Susanne, Wiercinska, Eliza, Krämer, Ariane, Stock, Belinda, Graff, Jochen, Martin, Hans, Wach, Achim, Escot, Christophe, Douglas, Garry, Romagnoli, Barbara, Chevalier, Eric, Dembowski, Klaus, Hooftman, Leon, Bonig, Halvard
Publicado no J Transl Med (2017)

Combined VEGF and CXCR4 antagonism targets the GBM stem cell population and synergistically improves survival in an intracranial mouse model of glioblastoma

Por Barone, Amy, Sengupta, Rajarshi, Warrington, Nicole M., Smith, Erin, Wen, Patrick Y., Brekken, Rolf A., Romagnoli, Barbara, Douglas, Garry, Chevalier, Eric, Bauer, Michael P., Dembowsky, Klaus, Piwnica-Worms, David, Rubin, Joshua B.
Publicado no Oncotarget (2014)

Efficacy of the Novel Antibiotic POL7001 in Preclinical Models of Pseudomonas aeruginosa Pneumonia

Por Cigana, Cristina, Bernardini, Francesca, Facchini, Marcella, Alcalá-Franco, Beatriz, Riva, Camilla, De Fino, Ida, Rossi, Alice, Ranucci, Serena, Misson, Pauline, Chevalier, Eric, Brodmann, Maj, Schmitt, Michel, Wach, Achim, Dale, Glenn E., Obrecht, Daniel, Bragonzi, Alessandra
Publicado no Antimicrob Agents Chemother (2016)

CXCR4 Protein Epitope Mimetic Antagonist, POL5551, Disrupts Metastasis and Enhances Chemotherapy Effect in Triple Negative Breast Cancer

Por Xiang, Jingyu, Hurchla, Michelle A., Fontana, Francesca, Su, Xinming, Amend, Sarah R., Esser, Alison K., Douglas, Garry J., Mudalagiriyappa, Chidananda, Luker, Kathryn E., Pluard, Timothy, Ademuyiwa, Foluso O., Romagnoli, Barbara, Tuffin, Gérald, Chevalier, Eric, Luker, Gary D., Bauer, Michael, Zimmermann, Johann, Aft, Rebecca L., Dembowsky, Klaus, Weilbaecher, Katherine N.
Publicado no Mol Cancer Ther (2015)