Efficacy of the Novel Antibiotic POL7001 in Preclinical Models of Pseudomonas aeruginosa Pneumonia

The clinical development of antibiotics with a new mode of action combined with efficient pulmonary drug delivery is a priority against untreatable Pseudomonas aeruginosa lung infections. POL7001 is a macrocycle antibiotic belonging to the novel class of protein epitope mimetic (PEM) molecules with...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Cigana, Cristina, Bernardini, Francesca, Facchini, Marcella, Alcalá-Franco, Beatriz, Riva, Camilla, De Fino, Ida, Rossi, Alice, Ranucci, Serena, Misson, Pauline, Chevalier, Eric, Brodmann, Maj, Schmitt, Michel, Wach, Achim, Dale, Glenn E., Obrecht, Daniel, Bragonzi, Alessandra
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2016
Assuntos:
Experimental Therapeutics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4958219/
https://ncbi.nlm.nih.gov/pubmed/27297477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00390-16
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