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Mechanistic Analysis of Cocrystal Dissolution as a Function of pH and Micellar Solubilization

[Image: see text] The purpose of this work is to provide a mechanistic understanding of the dissolution behavior of cocrystals under the influence of ionization and micellar solubilization. Mass transport models were developed by applying Fick’s law of diffusion to dissolution with simultaneous chem...

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Bibliografische gegevens
Gepubliceerd in:Mol Pharm
Hoofdauteurs: Cao, Fengjuan, Amidon, Gordon L., Rodriguez-Hornedo, Nair, Amidon, Gregory E.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Chemical Society 2016
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4783787/
https://ncbi.nlm.nih.gov/pubmed/26877267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.molpharmaceut.5b00862
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