Strand-invasion of duplex DNA by peptide nucleic acid oligomers.
Polyamide oligomers, termed peptide nucleic acids (PNAs), bind with high affinity to both DNA and RNA and offer both antisense and antigene approaches for regulating gene expression. When a PNA binds to a complementary sequence in a double-stranded DNA, one strand of the duplex is displaced, and a s...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1993
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC47834/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8248156/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.22.10648 |
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