Strand-invasion of duplex DNA by peptide nucleic acid oligomers.

Polyamide oligomers, termed peptide nucleic acids (PNAs), bind with high affinity to both DNA and RNA and offer both antisense and antigene approaches for regulating gene expression. When a PNA binds to a complementary sequence in a double-stranded DNA, one strand of the duplex is displaced, and a s...

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Detalles Bibliográficos
Main Authors: Peffer, N J, Hanvey, J C, Bisi, J E, Thomson, S A, Hassman, C F, Noble, S A, Babiss, L E
Formato: Artigo
Idioma:Inglês
Publicado: 1993
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC47834/
https://ncbi.nlm.nih.gov/pubmed/8248156
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