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Strand-invasion of duplex DNA by peptide nucleic acid oligomers.

Polyamide oligomers, termed peptide nucleic acids (PNAs), bind with high affinity to both DNA and RNA and offer both antisense and antigene approaches for regulating gene expression. When a PNA binds to a complementary sequence in a double-stranded DNA, one strand of the duplex is displaced, and a s...

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Bibliografische gegevens
Hoofdauteurs: Peffer, N J, Hanvey, J C, Bisi, J E, Thomson, S A, Hassman, C F, Noble, S A, Babiss, L E
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 1993
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC47834/
https://ncbi.nlm.nih.gov/pubmed/8248156
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