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Aneuploidy shortens replicative lifespan in Saccharomyces cerevisiae
Aneuploidy and aging are correlated; however, a causal link between these two phenomena has remained elusive. Here, we show that yeast disomic for a single native yeast chromosome generally have a decreased replicative lifespan. In addition, the extent of this lifespan deficit correlates with the si...
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| Publicado no: | Aging Cell |
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| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4783355/ https://ncbi.nlm.nih.gov/pubmed/26762766 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12443 |
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