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The Fitness Consequences of Aneuploidy Are Driven by Condition-Dependent Gene Effects
Aneuploidy is a hallmark of tumor cells, and yet the precise relationship between aneuploidy and a cell’s proliferative ability, or cellular fitness, has remained elusive. In this study, we have combined a detailed analysis of aneuploid clones isolated from laboratory-evolved populations of Saccharo...
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| Published in: | PLoS Biol |
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| Main Authors: | , , , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Public Library of Science
2015
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4444335/ https://ncbi.nlm.nih.gov/pubmed/26011532 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.1002155 |
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