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High-Throughput Identification of Adaptive Mutations in Experimentally Evolved Yeast Populations

High-throughput sequencing has enabled genetic screens that can rapidly identify mutations that occur during experimental evolution. The presence of a mutation in an evolved lineage does not, however, constitute proof that the mutation is adaptive, given the well-known and widespread phenomenon of g...

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Pubblicato in:PLoS Genet
Autori principali: Payen, Celia, Sunshine, Anna B., Ong, Giang T., Pogachar, Jamie L., Zhao, Wei, Dunham, Maitreya J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5065121/
https://ncbi.nlm.nih.gov/pubmed/27727276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1006339
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