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Specific protein homeostatic functions of small heat‐shock proteins increase lifespan
During aging, oxidized, misfolded, and aggregated proteins accumulate in cells, while the capacity to deal with protein damage declines severely. To cope with the toxicity of damaged proteins, cells rely on protein quality control networks, in particular proteins belonging to the family of heat‐shoc...
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| 發表在: | Aging Cell |
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| Main Authors: | , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
John Wiley and Sons Inc.
2015
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4783350/ https://ncbi.nlm.nih.gov/pubmed/26705243 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12422 |
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