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Specific protein homeostatic functions of small heat‐shock proteins increase lifespan
During aging, oxidized, misfolded, and aggregated proteins accumulate in cells, while the capacity to deal with protein damage declines severely. To cope with the toxicity of damaged proteins, cells rely on protein quality control networks, in particular proteins belonging to the family of heat‐shoc...
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| Publicado no: | Aging Cell |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4783350/ https://ncbi.nlm.nih.gov/pubmed/26705243 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12422 |
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