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Barcoding heat shock proteins to human diseases: looking beyond the heat shock response

There are numerous human diseases that are associated with protein misfolding and the formation of toxic protein aggregates. Activating the heat shock response (HSR) – and thus generally restoring the disturbed protein homeostasis associated with such diseases – has often been suggested as a therape...

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Autori principali: Kakkar, Vaishali, Meister-Broekema, Melanie, Minoia, Melania, Carra, Serena, Kampinga, Harm H.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Company of Biologists Limited 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3974453/
https://ncbi.nlm.nih.gov/pubmed/24719117
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.014563
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