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HSPA1A-Independent Suppression of PARK2 C289G Protein Aggregation by Human Small Heat Shock Proteins

The C289G mutation of the parkin E3-ubiquitin protein ligase (PARK2) is associated with autosomal recessive juvenile onset Parkinson's disease and was found to be associated with protein aggregation. Members of the human small heat shock proteins (HSPBs) have been implicated in protein degradat...

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Detalhes bibliográficos
Main Authors: Minoia, Melania, Grit, Corien, Kampinga, Harm H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4187737/
https://ncbi.nlm.nih.gov/pubmed/25022755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00698-14
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