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Drosophila phosphopantothenoylcysteine synthetase is required for tissue morphogenesis during oogenesis

BACKGROUND: Coenzyme A (CoA) is an essential metabolite, synthesized from vitamin B(5 )by the subsequent action of five enzymes: PANK, PPCS, PPCDC, PPAT and DPCK. Mutations in Drosophila dPPCS disrupt female fecundity and in this study we analyzed the female sterile phenotype of dPPCS mutants in det...

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Detalhes bibliográficos
Main Authors: Bosveld, Floris, Rana, Anil, Lemstra, Willy, Kampinga, Harm H, Sibon, Ody CM
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2542404/
https://ncbi.nlm.nih.gov/pubmed/18759961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-0500-1-75
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