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G Protein-Coupled Receptor Biased Agonism
G protein-coupled receptors (GPCR) are the largest family of targets for current therapeutics. The classic model of their activation was binary, where agonist binding induced an active conformation and subsequent downstream signaling. Subsequently, the revised concept of biased agonism emerged, wher...
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| 出版年: | J Cardiovasc Pharmacol |
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| 主要な著者: | , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2016
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4783281/ https://ncbi.nlm.nih.gov/pubmed/26751266 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/FJC.0000000000000356 |
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