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Direct observation of a 91 bp LacI-mediated, negatively supercoiled DNA loop by atomic force microscope
Escherichia coli lactose repressor (LacI), a tetrameric protein, is a paradigmatic transcriptional factor that controls the expression of lacZYA in the lac operon. It specifically binds to the O1, O2, and O3 operators of the lac promoter, forms DNA loops, and regulates transcription of the lac opero...
Gardado en:
| Publicado en: | FEBS Lett |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2016
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4783203/ https://ncbi.nlm.nih.gov/pubmed/26878689 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1873-3468.12094 |
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