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THE ANTIPSYCHOTIC POTENTIAL OF MUSCARINIC ALLOSTERIC MODULATION

The cholinergic hypothesis of schizophrenia emerged over 50 years ago based on clinical observations with both anticholinergics and pan-muscarinic agonists. Not until the 1990s did the cholinergic hypothesis of schizophrenia receive renewed enthusiasm based on clinical data with xanomeline, a muscar...

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Dettagli Bibliografici
Pubblicato in:Drug News Perspect
Autori principali: Bridges, Thomas M., LeBois, Evan P., Hopkins, Corey R., Wood, Michael R., Jones, Carrie K., Conn, P. Jeffrey, Lindsley, Craig W.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4780339/
https://ncbi.nlm.nih.gov/pubmed/20520852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1358/dnp.2010.23.4.1416977
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