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"Molecular Switches" on mGluR Allosteric Ligands That Modulate Modes of Pharmacology
[Image: see text] G-Protein-coupled receptors (GPCRs) represent the largest class of drug targets, accounting for more than 40% of marketed drugs; however, discovery efforts for many GPCRs have failed to provide viable drug candidates. Historically, drug discovery efforts have focused on developing...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3792571/ https://ncbi.nlm.nih.gov/pubmed/21341760 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi200129s |
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