"Molecular Switches" on mGluR Allosteric Ligands That Modulate Modes of Pharmacology

[Image: see text] G-Protein-coupled receptors (GPCRs) represent the largest class of drug targets, accounting for more than 40% of marketed drugs; however, discovery efforts for many GPCRs have failed to provide viable drug candidates. Historically, drug discovery efforts have focused on developing...

Full description

Saved in:
Bibliographic Details
Main Authors: Wood, Michael R., Hopkins, Corey R., Brogan, John T., Conn, P. Jeffrey, Lindsley, Craig W.
Format: Artigo
Language:Inglês
Published: 2011
Subjects:
Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3792571/
https://ncbi.nlm.nih.gov/pubmed/21341760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi200129s
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items