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"Molecular Switches" on mGluR Allosteric Ligands That Modulate Modes of Pharmacology

[Image: see text] G-Protein-coupled receptors (GPCRs) represent the largest class of drug targets, accounting for more than 40% of marketed drugs; however, discovery efforts for many GPCRs have failed to provide viable drug candidates. Historically, drug discovery efforts have focused on developing...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Wood, Michael R., Hopkins, Corey R., Brogan, John T., Conn, P. Jeffrey, Lindsley, Craig W.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2011
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3792571/
https://ncbi.nlm.nih.gov/pubmed/21341760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi200129s
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