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Naïve human pluripotent cells feature a methylation landscape devoid of blastocyst or germline memory
Human embryonic stem cells (hESCs) typically exhibit “primed” pluripotency, analogous to stem cells derived from the mouse post-implantation epiblast. This has led to a search for growth conditions that support self-renewal of hESCs akin to hypomethylated naïve epiblast cells in human pre-implantati...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | Cell Stem Cell |
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| Κύριοι συγγραφείς: | , , , , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
2016
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4779431/ https://ncbi.nlm.nih.gov/pubmed/26853856 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2016.01.019 |
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