Evidence for Intramyocardial Disruption of Lipid Metabolism and Increased Myocardial Ketone Utilization in Advanced Human Heart Failure

BACKGROUND: The failing human heart is characterized by metabolic abnormalities, but these defects remains incompletely understood. In animal models of HF there is a switch from a predominance of fatty acid utilization to the more oxygen-sparing carbohydrate metabolism. Recent studies have reported...

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Gepubliceerd in:Circulation
Hoofdauteurs: Bedi, Kenneth C., Snyder, Nathaniel W, Brandimarto, Jeffrey, Aziz, Moez, Mesaros, Clementina, Worth, Andrew J., Wang, Linda L., Javaheri, Ali, Blair, Ian A., Margulies, Kenneth, Rame, J. Eduardo
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2016
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4779339/
https://ncbi.nlm.nih.gov/pubmed/26819374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.115.017545
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