Epigenetic silencing of Th1 type chemokines shapes tumor immunity and immunotherapy

Epigenetic silencing including histone modifications and DNA methylation is an important tumorigenic mechanism(1) However, its role in cancer immunopathology and immunotherapy is poorly understood. Using ovarian cancers as our model, we found that enhancer of zeste homolog 2 (EZH2)-mediated histone...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Nature
मुख्य लेखकों: Peng, Dongjun, Kryczek, Ilona, Nagarsheth, Nisha, Zhao, Lili, Wei, Shuang, Wang, Weimin, Sun, Yuqing, Zhao, Ende, Vatan, Linda, Szeliga, Wojciech, Kotarski, Jan, Tarkowski, Rafał, Dou, Yali, Cho, Kathleen, Hensley-Alford, Sharon, Munkarah, Adnan, Liu, Rebecca, Zou, Weiping
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2015
विषय:
Article
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4779053/
https://ncbi.nlm.nih.gov/pubmed/26503055
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature15520
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