Defining Nicotinic Agonist Binding Surfaces through Photoaffinity Labeling()

Nicotinic acetylcholine (ACh) receptor (nAChR) agonists are potential therapeutic agents for neurological dysfunction. In the present study, the homopentameric mollusk ACh binding protein (AChBP), used as a surrogate for the extracellular ligand-binding domain of the nAChR, was specifically derivati...

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Pubblicato in:Biochemistry
Autori principali: Tomizawa, Motohiro, Maltby, David, Medzihradszky, Katalin F., Zhang, Nanjing, Durkin, Kathleen A., Presley, Jack, Talley, Todd T., Taylor, Palmer, Burlingame, Alma L., Casida, John E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2007
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4778401/
https://ncbi.nlm.nih.gov/pubmed/17614369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi700667v
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