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Defining Nicotinic Agonist Binding Surfaces through Photoaffinity Labeling()

Nicotinic acetylcholine (ACh) receptor (nAChR) agonists are potential therapeutic agents for neurological dysfunction. In the present study, the homopentameric mollusk ACh binding protein (AChBP), used as a surrogate for the extracellular ligand-binding domain of the nAChR, was specifically derivati...

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Dades bibliogràfiques
Publicat a:Biochemistry
Autors principals: Tomizawa, Motohiro, Maltby, David, Medzihradszky, Katalin F., Zhang, Nanjing, Durkin, Kathleen A., Presley, Jack, Talley, Todd T., Taylor, Palmer, Burlingame, Alma L., Casida, John E.
Format: Artigo
Idioma:Inglês
Publicat: 2007
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4778401/
https://ncbi.nlm.nih.gov/pubmed/17614369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi700667v
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