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Mapping the elusive neonicotinoid binding site

Two types of structurally similar nicotinic agonists have very different biological and physicochemical properties. Neonicotinoids, important insecticides including imidacloprid and thiacloprid, are nonprotonated and selective for insects and their nicotinic receptors, whereas nicotinoids such as ni...

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Detalhes bibliográficos
Main Authors: Tomizawa, Motohiro, Talley, Todd T., Maltby, David, Durkin, Kathleen A., Medzihradszky, Katalin F., Burlingame, Alma L., Taylor, Palmer, Casida, John E.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1885630/
https://ncbi.nlm.nih.gov/pubmed/17485662
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0703309104
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