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Atypical nicotinic agonist bound conformations conferring subtype selectivity
The nicotinic acetylcholine (ACh) receptor (nAChR) plays a crucial role in excitatory neurotransmission and is an important target for drugs and insecticides. Diverse nAChR subtypes with various subunit combinations confer differential selectivity for nicotinic drugs. We investigated the subtype sel...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2234212/ https://ncbi.nlm.nih.gov/pubmed/18230720 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0711724105 |
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