Nicotinic Agonist Binding Site Mapped by Methionine- and Tyrosine-Scanning Coupled with Azidochloropyridinyl Photoaffinity Labeling

Agonists activating nicotinic acetylcholine receptors (nAChR) include potential therapeutic agents and also toxicants such as epibatidine and neonicotinoid insecticides with a chloropyridinyl substituent. Nicotinic agonist interactions with mollusk (Aplysia californica) acetylcholine binding protein...

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Detalhes bibliográficos
Main Authors: Tomizawa, Motohiro, Talley, Todd T., Park, John F., Maltby, David, Medzihradszky, Katalin F., Durkin, Kathleen A., Cornejo-Bravo, Jose M., Burlingame, Alma L., Casida, John E., Taylor, Palmer
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2748672/
https://ncbi.nlm.nih.gov/pubmed/19459645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm900153c
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