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Soluble Aβ Oligomers Impair Hippocampal LTP by Disrupting Glutamatergic/GABAergic Balance

Epileptic activity may be more prevalent in early stage Alzheimer’s disease (AD) than previously believed. Several studies report spontaneous seizures and interictal discharges in mouse models of AD undergoing age-related Aβ accumulation. The mechanism by which Aβ-induced neuronal excitability can t...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Neurobiol Dis
Päätekijät: Lei, Ming, Xu, Huixin, Li, Zhangyuan, Wang, Zemin, O’Malley, Tiernan T., Zhang, Dainan, Walsh, Dominic M., Xu, Pingyi, Selkoe, Dennis J., Li, Shaomin
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2015
Aiheet:
Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4778388/
https://ncbi.nlm.nih.gov/pubmed/26525100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2015.10.019
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