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Environmental Novelty Activates β(2)-Adrenergic Signaling to Prevent the Impairment of Hippocampal LTP by Aβ Oligomers
A central question about human brain aging is whether cognitive enrichment slows the development of Alzheimer changes. Here we show that prolonged exposure to an enriched environment (EE) facilitated signaling in the hippocampus of wild-type mice that promoted long-term potentiation. A key feature o...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3596823/ https://ncbi.nlm.nih.gov/pubmed/23473322 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2012.12.040 |
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