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A mechanistic hypothesis for the impairment of synaptic plasticity by soluble Aβ oligomers from Alzheimer brain

It is increasingly accepted that early cognitive impairment in Alzheimer’s disease results in considerable part from synaptic dysfunction caused by the accumulation of a range of oligomeric assemblies of amyloid β-protein (Aβ). Most studies have used synthetic Aβ peptides to explore the mechanisms o...

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Detalhes bibliográficos
Publicado no:J Neurochem
Main Authors: Li, Shaomin, Selkoe, Dennis J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7487043/
https://ncbi.nlm.nih.gov/pubmed/32180217
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jnc.15007
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