A continuous sirtuin activity assay without any coupling to enzymatic or chemical reactions

Sirtuins are NAD(+) dependent lysine deacylases involved in many regulatory processes such as control of metabolic pathways, DNA repair and stress response. Modulators of sirtuin activity are required as tools for uncovering the biological function of these enzymes and as potential therapeutic agent...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Sci Rep
Egile Nagusiak: Schuster, Sabine, Roessler, Claudia, Meleshin, Marat, Zimmermann, Philipp, Simic, Zeljko, Kambach, Christian, Schiene-Fischer, Cordelia, Steegborn, Clemens, Hottiger, Michael O., Schutkowski, Mike
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group 2016
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4778124/
https://ncbi.nlm.nih.gov/pubmed/26940860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep22643
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