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A continuous sirtuin activity assay without any coupling to enzymatic or chemical reactions
Sirtuins are NAD(+) dependent lysine deacylases involved in many regulatory processes such as control of metabolic pathways, DNA repair and stress response. Modulators of sirtuin activity are required as tools for uncovering the biological function of these enzymes and as potential therapeutic agent...
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| 發表在: | Sci Rep |
|---|---|
| Main Authors: | , , , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Nature Publishing Group
2016
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4778124/ https://ncbi.nlm.nih.gov/pubmed/26940860 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep22643 |
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