Laddar...
mTORC1-mediated inhibition of polycystin-1 expression drives renal cyst formation in tuberous sclerosis complex
Previous studies report a cross-talk between the polycystic kidney disease (PKD) and tuberous sclerosis complex (TSC) genes. mTOR signalling is upregulated in PKD and rapamycin slows cyst expansion, whereas renal inactivation of the Tsc genes causes cysts. Here we identify a new interplay between th...
Sparad:
| I publikationen: | Nat Commun |
|---|---|
| Huvudupphovsmän: | , , , , , , , , , |
| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
Nature Publishing Group
2016
|
| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4778067/ https://ncbi.nlm.nih.gov/pubmed/26931735 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms10786 |
| Taggar: |
Lägg till en tagg
Inga taggar, Lägg till första taggen!
|