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Polycystin-1 Regulates Actomyosin Contraction and the Cellular Response to Extracellular Stiffness
Polycystin-1 (PC-1) and 2 (PC-2) are the products of the PKD1 and PKD2 genes, which are mutated in Autosomal Dominant Polycystic Kidney Disease (ADPKD). They form a receptor/channel complex that has been suggested to function as a mechanosensor, possibly activated by ciliary bending in the renal tub...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6851149/ https://ncbi.nlm.nih.gov/pubmed/31719603 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-53061-0 |
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