An Evaluation of the Crystal Structure of C-terminal Truncated Apolipoprotein A-I in Solution Reveals Structural Dynamics Related to Lipid Binding

Apolipoprotein (apo) A-I mediates many of the anti-atherogenic functions attributed to high density lipoprotein. Unfortunately, efforts toward a high resolution structure of full-length apoA-I have not been fruitful, although there have been successes with deletion mutants. Recently, a C-terminal tr...

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Udgivet i:J Biol Chem
Main Authors: Melchior, John T., Walker, Ryan G., Morris, Jamie, Jones, Martin K., Segrest, Jere P., Lima, Diogo B., Carvalho, Paulo C., Gozzo, Fábio C., Castleberry, Mark, Thompson, Thomas B., Davidson, W. Sean
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2016
Fag:
Protein Structure and Folding
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4777873/
https://ncbi.nlm.nih.gov/pubmed/26755744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.706093
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