An Evaluation of the Crystal Structure of C-terminal Truncated Apolipoprotein A-I in Solution Reveals Structural Dynamics Related to Lipid Binding

Apolipoprotein (apo) A-I mediates many of the anti-atherogenic functions attributed to high density lipoprotein. Unfortunately, efforts toward a high resolution structure of full-length apoA-I have not been fruitful, although there have been successes with deletion mutants. Recently, a C-terminal tr...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:J Biol Chem
Κύριοι συγγραφείς: Melchior, John T., Walker, Ryan G., Morris, Jamie, Jones, Martin K., Segrest, Jere P., Lima, Diogo B., Carvalho, Paulo C., Gozzo, Fábio C., Castleberry, Mark, Thompson, Thomas B., Davidson, W. Sean
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: American Society for Biochemistry and Molecular Biology 2016
Θέματα:
Protein Structure and Folding
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4777873/
https://ncbi.nlm.nih.gov/pubmed/26755744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.706093
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