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Helical domains that mediate lipid solubilization and ABCA1-specific cholesterol efflux in apolipoproteins C-I and A-II
Many of the apolipoproteins in HDL can elicit cholesterol efflux via ABCA1, a critical initial step in HDL formation. Recent work has indicated that omnipresent amphipathic helices play a critical role, and these have been studied intensively in the most common HDL protein, apolipoprotein (apo)A-I....
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Fformat: | Artigo |
Iaith: | Inglês |
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The American Society for Biochemistry and Molecular Biology
2013
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Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3679395/ https://ncbi.nlm.nih.gov/pubmed/23620136 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M037903 |
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