An Evaluation of the Crystal Structure of C-terminal Truncated Apolipoprotein A-I in Solution Reveals Structural Dynamics Related to Lipid Binding

Apolipoprotein (apo) A-I mediates many of the anti-atherogenic functions attributed to high density lipoprotein. Unfortunately, efforts toward a high resolution structure of full-length apoA-I have not been fruitful, although there have been successes with deletion mutants. Recently, a C-terminal tr...

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Dettagli Bibliografici
Pubblicato in:J Biol Chem
Autori principali: Melchior, John T., Walker, Ryan G., Morris, Jamie, Jones, Martin K., Segrest, Jere P., Lima, Diogo B., Carvalho, Paulo C., Gozzo, Fábio C., Castleberry, Mark, Thompson, Thomas B., Davidson, W. Sean
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2016
Soggetti:
Protein Structure and Folding
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4777873/
https://ncbi.nlm.nih.gov/pubmed/26755744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.706093
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