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The Crystal Structure of the C-Terminal Truncated Apolipoprotein A-I Sheds New Light on Amyloid Formation by the N-Terminal Fragment

Apolipoprotein A-I (apoA-I) is the main protein of plasma high-density lipoproteins (HDL, or good cholesterol) that remove excess cell cholesterol and protect against atherosclerosis. In hereditary amyloidosis, mutations in apoA-I promote its proteolysis and the deposition of the 9–11 kDa N-terminal...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Biochemistry
Egile Nagusiak: Gursky, Olga, Mei, Xiaohu, Atkinson, David
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2011
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4442606/
https://ncbi.nlm.nih.gov/pubmed/22229410
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi2017014
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