An Evaluation of the Crystal Structure of C-terminal Truncated Apolipoprotein A-I in Solution Reveals Structural Dynamics Related to Lipid Binding

Apolipoprotein (apo) A-I mediates many of the anti-atherogenic functions attributed to high density lipoprotein. Unfortunately, efforts toward a high resolution structure of full-length apoA-I have not been fruitful, although there have been successes with deletion mutants. Recently, a C-terminal tr...

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Dades bibliogràfiques
Publicat a:J Biol Chem
Autors principals: Melchior, John T., Walker, Ryan G., Morris, Jamie, Jones, Martin K., Segrest, Jere P., Lima, Diogo B., Carvalho, Paulo C., Gozzo, Fábio C., Castleberry, Mark, Thompson, Thomas B., Davidson, W. Sean
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2016
Matèries:
Protein Structure and Folding
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4777873/
https://ncbi.nlm.nih.gov/pubmed/26755744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.706093
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