An Evaluation of the Crystal Structure of C-terminal Truncated Apolipoprotein A-I in Solution Reveals Structural Dynamics Related to Lipid Binding

Apolipoprotein (apo) A-I mediates many of the anti-atherogenic functions attributed to high density lipoprotein. Unfortunately, efforts toward a high resolution structure of full-length apoA-I have not been fruitful, although there have been successes with deletion mutants. Recently, a C-terminal tr...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Melchior, John T., Walker, Ryan G., Morris, Jamie, Jones, Martin K., Segrest, Jere P., Lima, Diogo B., Carvalho, Paulo C., Gozzo, Fábio C., Castleberry, Mark, Thompson, Thomas B., Davidson, W. Sean
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2016
Assuntos:
Protein Structure and Folding
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4777873/
https://ncbi.nlm.nih.gov/pubmed/26755744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.706093
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