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Romk1 Knockout Mice Do Not Produce Bartter Phenotype but Exhibit Impaired K Excretion
Romk knock-out mice show a similar phenotype to Bartter syndrome of salt wasting and dehydration due to reduced Na-K-2Cl-cotransporter activity. At least three ROMK isoforms have been identified in the kidney; however, unique functions of any of the isoforms in nephron segments are still poorly unde...
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| Опубликовано в: : | J Biol Chem |
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| Главные авторы: | , , , , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Society for Biochemistry and Molecular Biology
2016
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4777858/ https://ncbi.nlm.nih.gov/pubmed/26728465 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.707877 |
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