ROMK1 channel activity is regulated by monoubiquitination

The ubiquitination of proteins can signal their degradation, modify their activity or target them to specific membranes or cellular organelles. Here, we show that monoubiquitination regulates the plasma membrane abundance and function of the potassium channel, ROMK. Immunoprecipitation of proteins o...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Lin, Dao-Hong, Sterling, Hyacinth, Wang, Zhijian, Babilonia, Elisa, Yang, Baofeng, Dong, Ke, Hebert, Steven C., Giebisch, Gerhard, Wang, Wen-Hui
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2005
Schlagworte:
Biological Sciences
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC555508/
https://ncbi.nlm.nih.gov/pubmed/15767585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0409767102
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