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Protein Kinase C (PKC)-induced Phosphorylation of ROMK1 Is Essential for the Surface Expression of ROMK1 Channels

We carried out in vitro phosphorylation assays to determine whether ROMK1 is a substrate of protein kinase C (PKC) and used the two-electrode voltage clamp method to investigate the role of serine residues 4, 183, and 201, the three putative PKC phosphorylation sites, in the regulation of ROMK1 chan...

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Detalhes bibliográficos
Main Authors: Lin, DaoHong, Sterling, Hyacinth, Lerea, Kenneth M., Giebisch, Gerhard, Wang, Wen-Hui
Formato: Artigo
Idioma:Inglês
Publicado em: 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3047507/
https://ncbi.nlm.nih.gov/pubmed/12221079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M203702200
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