Absence of Small Conductance K(+) Channel (SK) Activity in Apical Membranes of Thick Ascending Limb and Cortical Collecting Duct in ROMK (Bartter’s) Knockout Mice

The ROMK (Kir1.1; Kcnj1) gene is believed to encode the apical small conductance K(+) channels (SK) of the thick ascending limb (TAL) and cortical collecting duct (CCD). Loss-of-function mutations in the human ROMK gene cause Bartter’s syndrome with renal Na(+) wasting, consistent with the role of t...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Gepubliceerd in:J Biol Chem
Hoofdauteurs: Lu, Ming, Wang, Tong, Yan, Qingshang, Yang, Xinbo, Dong, Ke, Knepper, Mark A., Wang, WenHui, Giebisch, Gerhard, Shull, Gary E., Hebert, Steven C.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2002
Onderwerpen:
Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4426997/
https://ncbi.nlm.nih.gov/pubmed/12130653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M206644200
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!

Gelijkaardige items