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Urinary bladder hypertrophy characteristic of male ROMK Bartter’s mice does not occur in female mice
The renal outer medullary potassium channel (ROMK; K(ir)1.1) plays an important role in Na(+) and K(+) homeostasis. ROMK knockout (KO) mice show a similar phenotype to Bartter’s syndrome of salt wasting and dehydration due to reduced Na-2Cl-K-cotransporter activity but not in ROMK1 KO mice. ROMK KO...
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| Veröffentlicht in: | Am J Physiol Regul Integr Comp Physiol |
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| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Physiological Society
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5899254/ https://ncbi.nlm.nih.gov/pubmed/29092859 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpregu.00315.2017 |
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