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Stimulating the Release of Exosomes Increases the Intercellular Transfer of Prions

Exosomes are small extracellular vesicles released by cells and play important roles in intercellular communication and pathogen transfer. Exosomes have been implicated in several neurodegenerative diseases, including prion disease and Alzheimer disease. Prion disease arises upon misfolding of the n...

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Detalles Bibliográficos
Publicado en:J Biol Chem
Autores principales: Guo, Belinda B., Bellingham, Shayne A., Hill, Andrew F.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2016
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4777847/
https://ncbi.nlm.nih.gov/pubmed/26769968
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.684258
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