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The Neutral Sphingomyelinase Pathway Regulates Packaging of the Prion Protein into Exosomes
Prion diseases are a group of transmissible, fatal neurodegenerative disorders associated with the misfolding of the host-encoded prion protein, PrP(C), into a disease-associated form, PrP(Sc). The transmissible prion agent is principally formed of PrP(Sc) itself and is associated with extracellular...
Uloženo v:
| Vydáno v: | J Biol Chem |
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| Hlavní autoři: | , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
American Society for Biochemistry and Molecular Biology
2015
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4319014/ https://ncbi.nlm.nih.gov/pubmed/25505180 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.605253 |
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