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The Neutral Sphingomyelinase Pathway Regulates Packaging of the Prion Protein into Exosomes
Prion diseases are a group of transmissible, fatal neurodegenerative disorders associated with the misfolding of the host-encoded prion protein, PrP(C), into a disease-associated form, PrP(Sc). The transmissible prion agent is principally formed of PrP(Sc) itself and is associated with extracellular...
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| Publié dans: | J Biol Chem |
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| Auteurs principaux: | , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Society for Biochemistry and Molecular Biology
2015
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4319014/ https://ncbi.nlm.nih.gov/pubmed/25505180 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.605253 |
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