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Small RNA deep sequencing reveals a distinct miRNA signature released in exosomes from prion-infected neuronal cells

Prion diseases are transmissible neurodegenerative disorders affecting both humans and animals. The cellular prion protein, PrP(C), and the abnormal infectious form, PrP(Sc), are found associated with exosomes, which are small 50–130 nm vesicles released from cells. Exosomes also contain microRNAs (...

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Detalhes bibliográficos
Main Authors: Bellingham, Shayne A., Coleman, Bradley M., Hill, Andrew F.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2012
Assuntos:
RNA
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3505968/
https://ncbi.nlm.nih.gov/pubmed/22965126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks832
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