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Small RNA deep sequencing reveals a distinct miRNA signature released in exosomes from prion-infected neuronal cells
Prion diseases are transmissible neurodegenerative disorders affecting both humans and animals. The cellular prion protein, PrP(C), and the abnormal infectious form, PrP(Sc), are found associated with exosomes, which are small 50–130 nm vesicles released from cells. Exosomes also contain microRNAs (...
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| Autori principali: | , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Oxford University Press
2012
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3505968/ https://ncbi.nlm.nih.gov/pubmed/22965126 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks832 |
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